Back to Games

Dr. Mario

NES Retro Game

Loading Dr. Mario...

Optimized for 640×600

Controls:

WASD: D-pad

J: B button, K: A button, L: A+B

U: B rapid, I: A rapid, O: A+B rapid

V: BB rapid, C: AA rapid

Enter: Start, Ctrl: Select

Dr. Mario

Mario trades his overalls for a lab coat in this addictive puzzle game! Match colored pills to eliminate viruses in this Tetris-style challenge. With its catchy music, strategic gameplay, and increasing difficulty, Dr. Mario provides hours of brain-teasing fun that's easy to learn but hard to master.

NES Classic640×600SquareCompact

Game Controls

Classic NES game controls - experience retro gaming at its finest!

↑ ↓ ← → / WASDD-Pad (Move)
X / KA Button
Z / JB Button
LA+B Combo
IA Rapid Fire
UB Rapid Fire
OA+B Rapid Fire
EnterStart
CtrlSelect

NES Gaming Tips

  • • Click anywhere on the game to enable audio
  • • Use fullscreen for the best retro gaming experience
  • • Some games may require both A and B buttons
  • • Try different button combinations for special moves

Having trouble? Try refreshing the page or using fullscreen mode for the best experience.

Enjoying this game? Check out our other free unblocked games!